Anticholinergic use for more than 3 months Increased risk of dementia

A recent literature review of the long-term use of anticholinergic drugs used to treat overactive bladder symptoms, showed an increase risk of dementia by an average of 46%. Anticholinergic drugs include oxybutynin, solifenacin, darifenacin, tolterodine and trospium. ( Neurology and urodynamics 2021;40:15-24 )